Can an excema be stress-induced

Eczema and stress

04/01/2008 | Leading theme | Edition 4/2008

How do feelings get into the skin?

Magazine:
The dermatologist> issue 4/2008
Authors:
A.V. Mitschenko, A.N. Lwow, J. Kupfer, V. Niemeier, Prof. Dr. U. Gieler

Summary

It is generally assumed that stress has an influence on the development or at least worsening of atopic dermatitis. The psychoimmunological mechanisms of how skin inflammation develops due to stress are not yet entirely clear. However, this topic has been intensively researched in recent years, and the studies deal with various explanatory aspects: neuroimmunological, psychoendocrinological studies and studies of the integrity and function of the skin barrier under stress. Various neuropeptides and neurotrophins seem to play an important role in stress-induced neurogenic inflammatory processes and the connection between the nervous and immune systems. Mast cells play a key role in the development of inflammatory responses to stress. The skin barrier is destroyed under stress conditions by increasing the cortisol level. The formation of lamellar bodies is reduced and the epidermal expression of antimicrobial peptides (β-defensin and cathelicidin) is inhibited. This article provides an overview of the current research aspects.

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literature
Go back to reference Lonne-Rahm S, Berg M, Mårin P, Nordlind K (2004) Atopic dermatitis, stinging, and effects of chronic stress: a pathocausal study. J Am Acad Dermatol 51 (6): 899-905 PubMedCrossRef Lonne-Rahm S, Berg M, Mårin P, Nordlind K (2004) Atopic dermatitis, stinging, and effects of chronic stress: a pathocausal study. J Am Acad Dermatol 51 (6): 899-905 PubMedCrossRef
About this article
title
Eczema and stress
How do feelings get into the skin?
Authors:
A.V. Mitchenko
AT. Lwow
J. Copper
V. Niemeier
Prof. Dr. U. Gieler
Publication date
01.04.2008
DOI
https://doi.org/10.1007/s00105-008-1525-z
magazine
The dermatologist's journal of dermatology, venereology and related fields
Edition 4/2008
Print ISSN: 0017-8470
Electronic ISSN: 1432-1173
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