What is the side effect of cortisone

W.interesting facts about cortisone

Cortisone is indispensable. It helps to treat acute inflammatory processes and quickly restore function. It improves rheumatic pain very quickly and also has a slightly euphoric effect. The very good effectiveness should not hide the fact that cortisone causes a number of side effects, especially when used too much and improperly. Your rheumatologist will therefore always endeavor to keep the cortisone dose as low as possible and prefer to give a second drug that has fewer side effects in the long term (e.g. methotrexate, azathioprine, etc.).

Important side effects of cortisone

  • Changes in body shape such as bull neck, full moon face, trunk obesity.
  • Muscle atrophy, cortisone myopathy (pain in the muscles).
  • Changes in metabolism with a tendency to diabetes and disorders of lipid metabolism.
  • Influencing the vessels in the direction of arteriosclerosis, developing high blood pressure.
  • Increase in the risk of thrombosis.
  • Adrenal insufficiency, i.e. the inability to respond adequately to stress.
  • Dependence on daily intake. If you have been taking cortisone for a long time, this drug should not be stopped immediately. There should be a tapering off.
  • Development before osteoporosis. Vitamin D should be prescribed for doses above 7.5 mg. Sport is also an effective prophylaxis against osteoporosis.
  • Stomach ulcers can develop especially when anti-inflammatory pain relievers and cortisone are taken together.

There are different cortisone supplements with varying degrees of effectiveness. That is why the term des Prednisolone equivalent introduced. For example, 4 mg methylprednisolone are just as effective and have side effects as 5 mg prednisolone.

A cortisone preparation should be taken between 6 a.m. and 8 a.m. or even earlier, which is very close to the physiological, i.e. natural, cortisone cycle. If, in rare cases, the cortisone dose has to be divided into a morning and an evening dose (“split”), 2/3 of the cortisone dose should be taken in the morning. A so-called night cortisone is available for patients with severe morning stiffness in rheumatoid arthritis. This is taken around 10 p.m. and prevents the formation of inflammatory messenger substances, which are often released between 4 a.m. and 6 a.m. in the morning. This cortisone can be prescribed instead of the morning cortisone.